List of New AntiCancer Medication, Drugs and Side Effects

Anticancer, or antineoplastic, drugs are used to treat malignancies, or cancerous growths. Drug therapy may be used alone, or in combination with other treatments such as surgery or radiation therapy.
anti cancer drugs

Anticancer drugs are used to control the growth of cancerous cells.
Cancer is commonly defined as the uncontrolled growth of cells, with loss of differentiation and commonly, with metastasis, spread of the cancer to other tissues and organs. Cancers are malignant growths. In contrast, benign growths remain encapsulated and grow within a well-defined area. Although benign tumors may be fatal if untreated, due to pressure on essential organs, as in the case of a benign brain tumor, surgery or radiation are the preferred methods of treating growths which have a well defined location. Drug therapy is used when the tumor has spread, or may spread, to all areas of the body.

Several classes of drugs may be used in cancer treatment, depending on the nature of the organ involved. For example, breast cancers are commonly stimulated by estrogens, and may be treated with drugs that inactivate the sex hormones. Similarly, prostate cancer may be treated with drugs that inactivate androgens, the male sex hormone. However, the majority of antineoplastic drugs act by interfering with cell growth. Since cancerous cells grow more rapidly than other cells, the drugs target those cells that are in the process of reproducing themselves. As a result, antineoplastic drugs will commonly affect not only the cancerous cells, but others cells that commonly reproduce quickly, including hair follicles, ovaries and testes, and the blood-forming organs.
Newer methods of antineoplastic drug therapy have taken different approaches, including angiogenesis—the inhibition of formation of blood vessels feeding the tumor and contributing to tumor growth. Although these approaches hold promise, they are not yet in common use. Developing new anticancer drugs is the work of ongoing research. In 2003, a new technique was developed to streamline the search for effective drugs. Researchers pumped more than 23,000 chemical compounds through a screening technique to identify those that help fight cancer while leaving healthy cells unharmed. The system identified nine compounds matching the profile, including one previously unidentified drug for fighting cancer. They have expanded their research to determine how the drug might be developed. This was an important step

Anti Cancer Drugs

  • Altretamine (Hexalen) Treatment of advanced ovarian cancer Side Effects: Bone marrow depression, nausea and vomiting
  • Asparaginase (Elspar) Commonly used in combination with other drugs; refractory acute lymphocytic leukemia Liver, kidney, pancreas, CNS abnormalities, Bleomycin (Blenoxane) Lymphomas, Hodgkin’s disease,testicular cancer Side Effects: Hair loss, stomatitis, pulmonary toxicity, hyperpigmentation
    of skin
  • Busulfan (Myleran) Chronic granulocytic leukemia Side Effects: Bone marrow depression, pulmonary toxicity
  • Carboplatin (Paraplatin) Pallilation of ovarian cancer Side Effects:Bone marrow depression, nausea and vomiting
  • Carmustine Hodgkin’s disease, brain tumors, multiple myeloma, malignant melonoma Side Effects: Bone marrow depression, nausea and vomiting, toxic damage to liver
  • Chlorambucil (Leukeran) Chronic lymphocytic leukemia, nonHodgkin’s
    lymphomas, breast and ovarian cancer Side Effects: Bone marrow depression, excess uric acid in blood
  • Cisplatin (Platinol) Treatment of bladder, ovarian, uterine, testicular,
    head and neck cancers Side Effects: Renal toxicity and ototoxicity
  • Cladribine (Leustatin) Hairy cell leukemia Side Effects:Bone marrow depression, nausea and vomiting, fever
  • Cyclophosphamide(Cytoxan) Hodgkin’s disease, non-Hodgkin’s lymphomas, neuroblas-
    toma. Often used with other drugs for breast, ovarian, and lung cancers; acute
    lymphoblastic leukemia in children; multiple myeloma Side Effects: Bone marrow
    depression, hair loss, nausea and vomiting, inflammation of the bladder
  • Cytarabine (Cytosar-U) Leukemias occurring in adults and children Side Effects: Bone marrow depression, nausea and vomiting,diarrhea, stomatitis
  • Dacarbazine (DTIC-Dome) Hodgkin’s disease, malignant melanoma Side Effects:Bone marrow depression, nausea and vomiting
  • Diethylstilbestrol (DES) (Stilbestrol) Breast cancer in post-menopausal
    women, prostate cancer Side Effects: Hair loss, nausea and
    vomiting, edema,excess calcium in blood; feminizing effects in men
  • Ethinyl estradiol (Estinyl) Advanced breast cancer in post-menopausal women,
    prostate cancer Side Effects: Excess calcium in blood, anorexia,
    edema, nausea and vomiting; feminizing effects in men
  • Etoposide (VePesid) Acute leukemias, lymphomas, testicular cancer Side Effects:Bone marrow depression, nausea and vomiting, hair loss
  • Mitomycin (Mutamycin) Bladder, breast, colon, lung, pancreas, rectum
    cancers, head and neck cancer, malignant melanoma Side Effects:Bone marrow
    depression, nausea and vomiting, diarrhea, stomatitis, possible tissue damage
  • Mitotane (Lysodren) Cancer of the adrenal cortex (inoperable) Side Effects:Damage to adrenal cortex, nausea, anorexia
  • Mitoxantrone (Novantrone) Acute nonlymphocy-
    tic leukemia Cardiac arrhythmias Side Effects: labored breathing,
    nausea and vomiting, diarrhea, fever, congestive heart failure
  • Paclitaxel (Taxol) Advanced ovarian cancer Side Effects: Bone marrow
    depression, hair loss, nausea and vomiting, hypotension, allergic
    reactions, slow heart action, muscle and joint pain
  • Pentastatin (Nipent) Hairy cell leukemia unresponsive to alpha-interferon Side Effects:Bone marrow depression, fever, skin rash, liver damage, nausea and
    vomiting
  • Pipobroman (Vercyte) Chronic granulocytic leukemia Side Effects: Bone marrow
    depression
  • Plicamycin (Mithracin) Testucular tumors Side Effects:Toxicity/damage
    to bone marrow, kidneys, and liver
  • Prednisone (Meticorten) Used in adjunct therapy for palliation of
    symptoms in lymphomas, acute leukemia Hodgkin’s disease Side Effects: May be toxic to all body systems
  • Procarbazine (Matulane) Hodgkin’s disease Side Effects: Bone marrow
    depression, nausea and vomiting
  • Streptozocin (Zanosar) Islet cell carcinoma of pancreas Side Effects:Nausea and vomiting, toxicity to kidneys
  • Tamoxifen (Nolvadex) Advanced breast cancer in post menopausal Side Effects:Nausea and vomiting, ocular toxicity, hot flashes
  • Teniposide (Vumon) Acute lymphocytic leukemia in children
  • Vinblastine (Velban) Breast cancer, Hodgkin’s disease, metastatic testicular
    cancer Side Effects: Bone marrow depression, neurotoxicity
  • Vincristine (Oncovin) Acute leukemia, Hodgkin’s disease, lymphomas Side Effects:Constipation, neurotoxicity, possible tissue necrosis